Morphological Distribution Patterns and Neuroimmune Communication of Ganglia in Molly Fish (Poecilia sphenops, Valenciennes 1846)

Twenty-four adult molly fish (Poecilia sphenops, Valenciennes 1846) were collected to study the morphology and distribution of ganglia using histological, immunohistochemical, electron microscopy focusing on their relation immune cells. The classified spatially into cranial spinal, functionally sensory autonomic. Spinal (dorsal root ganglia, DRG) contained large close ganglionic cells, enclosed by satellite as well bundles both myelinated non-myelinated nerve fibers. There are glial cells telocytes ganglion. In addition, oligodendrocytes closely related axons. Glial fibrillary acidic protein (GFAP) expression was confined glia fibers in cervical next gills, surprisingly, DRG. vestibular large, connected hind brain, numerous neurons packed columns. observed around pseudobranch, head kidney, thymus. Their randomly distributed, peripherally situated. CD3-positive T-lymphocytes, dendritic CD68-positive macrophages contact with ganglia. Furthermore, kidney showed positive Iba1-expressing Most ganglion DRG, autonomic, moderate strong S-100 immunoreactivity. enteric glia, CD68-expressing macrophages, acetylcholine (Ach)-expressing along muscular layer intestinal wall. conclusion, different displayed direct communication which support maintain healthy